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  1. 紀要
  2. 純真学園大学雑誌
  3. 第01号~第10号
  4. 第2号(2012)

Protective Effects of Enterococcus Faecalis 2001 (EF 2001) against Radiation-induced Leukocytes Damage in Mice

https://junshin.repo.nii.ac.jp/records/79
https://junshin.repo.nii.ac.jp/records/79
4a674c7c-56f5-4ff0-8800-e2ab203462eb
名前 / ファイル ライセンス アクション
純真学園大学雑誌-02号_p055-061.pdf 純真学園大学雑誌-02号_p055-061 (193.2 kB)
license.icon
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-10-05
言語
言語 jpn
キーワード
言語 en
主題Scheme Other
主題 Radiation protection
キーワード
言語 en
主題Scheme Other
主題 Lymphocyte
キーワード
言語 en
主題Scheme Other
主題 CD4
キーワード
言語 en
主題Scheme Other
主題 CD8
キーワード
言語 en
主題Scheme Other
主題 CD16
キーワード
言語 en
主題Scheme Other
主題 Enterococcus Faecalis
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ departmental bulletin paper
著者 Gu, Yeun-Hwa

× Gu, Yeun-Hwa

Gu, Yeun-Hwa

en Gu, Yeun-Hwa

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Kang, Ki-Mun

× Kang, Ki-Mun

Kang, Ki-Mun

en Kang, Ki-Mun

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Iwasa, Masahiro

× Iwasa, Masahiro

Iwasa, Masahiro

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Iwasa, Masahiro

× Iwasa, Masahiro

en Iwasa, Masahiro

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内容記述
内容記述タイプ Other
内容記述 Abstract : Radiation protection from death and decrease damage leukocyte recovery by oral administrations consecutively of EF 2001 (Enterococcus Faecalis 2001), 200 mg/kg b.w., once a day, before whole-body x-rays irradiation was confirmed by tests with C3H mice, meanwhile, its radioprotective actions compared to immunological enhancement. Based on the studies of survival, behavior of hematograms, and numbers of lymphocytes, whole body following irradiation, it was demonstrated that EF 2001 was an effective radioprotector. The survival of irradiated mice protected by EF 2001 was significantly increased and statistically higher than that of mice pre-treated with oral administration. After administration of EF 2001, promoted recovery of leukocyte and lymphocytes counts were observed in mice pre-treated with EF 2001. All above-mentioned results were similar to those in mice protected by EF 2001, but the protecting actions of EF 2001 on promoting recovery of nucleated cells and leukocyte counts were significantly higher than those of EF 2001. It could be deduced that the uncertain radioprotective action against death is induced by a possible process of enhanced regeneration of the leukocyte stem cells due to not only strengthened radioresistance and increased numbers of remained leukocyte cells, but also enhanced post-irradiation repair or promoted prolif-eration of the leukocyte stem cells. This effect of EF 2001 may have some therapeutic implications for radiation-induced injuries. Showing in this paper. In addition, we think that indicating the activation of cell-mediated immune responses.
書誌情報 純真学園大学雑誌
en : Journal of Junshin Gakuen University, Faculty of Health Sciences

号 2, p. 055-061, 発行日 2013-03
出版者
出版者 純真学園大学
ISSN
収録物識別子タイプ ISSN
収録物識別子 2186-6481
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA12581584
論文ID(NAID)
関連タイプ isIdenticalTo
識別子タイプ NAID
関連識別子 40019816356
フォーマット
内容記述タイプ Other
内容記述 application/pdf
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
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